La revisión y análisis de los casos de tumor de estirpe ependimaria, según verificación neuropatólogica,operados en hospitales de Maracaibo, Venezuela, con la finalidad de comparar contrastar nuestros resultados con otros previamente publicados.
Material y métodosSe revisaron las historias clínicas correspondientes a 53 pacientes con diagnóstico de tumor de estirpe ependimaria intervenidos diferentes hospitales de Maracaibo durante el período 1° de Julio de 1990 - 30 de Junio de 1998. Las variables analizadas incluyeron edad, genero, localización tumoral y diagnedad, género,stico definitivo. Desde el punto vista neuropatológico las lesiones se clasificaron en subependimoma, ependimoma clásico, ependimoma mixopapilar, ependimoma anaplásico y tumor primitivo neuroectodérmico con diferenciación ependimaria (ependimoblastoma).
ResultadosLas lesiones intracraneales el constituyeron 90.5% de los casos, de estas el 58.4% se consiguieron albergadas en el compartimento supratentorial. Los tumores originados en el cordón espinal representaron el 9.4% del total de los casos. La elocuencia clínica se hizo manifiesta en pacientes de las en pacientes de las primeras dos décadas de la vida en 58.4% de los casos.
ConclusionesLos ependimomas anaplásicos representaron la entidad más frecuente en la presente serie con una alta incidencia en niños y adolescentes.
To review and analyze the neuropatologically verified tumors of ependymal origin operated in Maracaibo (Venezuela) in order to compare our results with those reported by other authors.
Material and methodsThe clinical charts of 53 patients with the neuropathological diagnosis of ependymal derived tumor operated in different hospitals of Maracaibo between July 1st. 1990 and June 301998 were reviewed. The variables analyzed included age, gender, tumor location and histological diagnosis. From the neuropathological point of view tumors were classified as follows: subependymoma, classic ependymoma, myxopapillary ependymoma, anaplastic ependymoma, and primitive neuroectodermal tumor with ependymal differentiation (ependymoblastoma).
ResultsThe majority of the lesions (90.5%) were intracranial and 58.4% of these were located in the supratentorial compartment. Spinal cord neoplasms accounted for 9.4% of the present series. 58.4% of the tumors became clinically eloquent during the first two decades of life
ConclusionsAnaplastic ependymomas outnumbered the other variants showed a high incidence in childhood and adolescence.
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