Journal Information
Share
Download PDF
More article options
Clinical research
Uncorrected Proof. Available online 23 June 2025
Epileptogenicity post stereoelectroencephalography and subdural grids invasive monitoring: A retrospective analysis of adult and pediatric patients with refractory epilepsy
Epileptogenicidad después de estereoelectroencefalografía y monitorización invasiva de rejillas subdurales: un análisis retrospectivo de pacientes adultos y pediátricos con epilepsia refractaria
Sonia Pulidoa, Sven Ivankovicb,
, Nolan Winslowb, Andres Maldonadob
a University of Illinois College of Medicine at Peoria, IL, USA
b Department of Neurosurgery, OSF Saint Francis Medical Center, Peoria, IL, USA
Article information
Abstract
Full Text
Bibliography
Download PDF
Statistics
Tables (8)
Table 1. Patient demographics by group.
Tables
Table 2. Post invasive monitoring seizures by timeframe and group.
Tables
Table 3. Change in seizure frequency by group.
Tables
Table 4. Seizures per month by group and timeframe.
Tables
Table 5. Seizure frequency by group within timeframe.
Tables
Table 6. Monitored brain locations.
Tables
Table 7. Decrease in seizure frequency by brain region and group.
Tables
Table 8. Overall monthly seizure frequency descriptive statistics by brain region and timeframe before and after invasive monitoring.
Tables
Show moreShow less
Abstract
Objective

To assess if removal of stereoelectroencephalography (SEEG) or subdural grids (SDG) is associated with an increased seizure frequency in patients with refractory epilepsy during the immediate postoperative period.

Methods

37 patients with refractory epilepsy that underwent monitoring with SEEG or SDG during November 2012–March 2022 were identified using electronic medical records from a single institution. Seizure history, duration of intracranial monitoring, and monitored brain regions were recorded.

Results

5.0% and 5.9% of SEEG and SDG patients had a seizure within 48h post-termination of monitoring. 25% and 11.8% of SEEG and SDG patients had a seizure between 48h and 1-week after surgery. Between 1 week and 1 month after SEEG or SDG removal, 35% and 41.2% of patients had a seizure. 30% and 50% SEEG or SDG patients had a seizure between 1- and 2-months following removal. Overall change in postoperative seizure frequency was not significant. Seizure frequency increased for 11.8% of SDG patients while frequency remained unchanged for 5.9% and decreased for 82.4%. No patients post-SEEG removal in our cohort experienced an increased seizure frequency. 95% experienced a decrease in seizure frequency and no change was observed in 5%.

Conclusion

SEEG is not associated with increased epileptogenicity after termination of monitoring. Two patients post-SDG removal experienced an increase in seizure frequency. While patients with refractory epilepsy may continue to have seizures during the immediate postoperative period, it is likely that patients will experience a decrease in seizure frequency after removal of SEEG or SDG.

Keywords:
Epilepsy
Stereoelectroencephalography
Subdural grids
Seizure frequency
Abbreviations:
AED
EZ
FLAIR
MRI
PET
SDG
SDE
SEEG
SPECT
Resumen
Objectivo

Evaluar si la extirpación de la estereoelectroencefalografía (SEEG) o de las rejillas subdurales (SDG) se asocia con un aumento de la frecuencia de convulsiones en pacientes con epilepsia refractaria durante el período postoperatorio inmediato.

Métodos

Se identificaron 37 pacientes con epilepsia refractaria que se sometieron a seguimiento con SEEG o SDG durante Noviembre 2012 - Marzo 2022, utilizando historias clínicas electrónicas de una sola institución. Se registraron antecedentes convulsivos, duración de la monitorización intracraneal y regiones cerebrales monitoreadas.

Resultados

El 5,0% y el 5,9% de los pacientes con SEEG y SDG tuvieron convulsiones dentro de las 48 horas posteriores a la terminación del seguimiento. El 25% y el 11,8% de los pacientes con SEEG y SDG tuvieron convulsiones entre 48 horas y 1 semana después de la cirugía. Entre 1 semana y 1 mes después de la extirpación del SEEG o del SDG, el 35% y el 41,2% de los pacientes presentaron con convulsiones. El 30% y el 50% de los pacientes con SEEG o SDG tuvieron una convulsión entre 1 y 2 meses después de la extirpación. El cambio general en la frecuencia de convulsiones postoperatorias no fue significativo. La frecuencia de convulsiones aumentó en 11,8% de los pacientes con SDG, mientras que la frecuencia permaneció sin cambios en 5,9% y disminuyó en 82,4%. Ningún paciente después de la extirpación del SEEG en nuestra cohorte experimentó un aumento de la frecuencia de convulsiones. El 95% experimentó una disminución en la frecuencia de convulsiones y no se observó ningún cambio en el 5%.

Conclusión

El SEEG no se asocia con un aumento de la epileptogenicidad después de la terminación de la monitorización. Dos pacientes después de la extirpación del SDG experimentaron un aumento en la frecuencia de convulsiones. Mientras que los pacientes con epilepsia refractaria pueden continuar teniendo convulsiones durante el período postoperatorio inmediato, es probable que los pacientes experimenten una disminución en la frecuencia de convulsiones después de la extracción de SEEG o SDG.

Palabras clave:
Frecuencia de las convulsions
Epilepsia
Estereoelectroencefalografía
Rejillas subdurales

Article

These are the options to access the full texts of the publication Neurocirugía (English edition)
Member
Member of the Sociedad Española de Neurocirugía

If it is the first time you have accessed you can obtain your credentials by contacting Elsevier Spain in suscripciones@elsevier.com or by calling our Customer Service at902 88 87 40 if you are calling from Spain or at +34 932 418 800 (from 9 to 18h., GMT + 1) if you are calling outside of Spain.

If you already have your login data, please click here .

If you have forgotten your password you can you can recover it by clicking here and selecting the option ¿I have forgotten my password¿.

Subscriber
Subscriber

If you already have your login data, please click here .

If you have forgotten your password you can you can recover it by clicking here and selecting the option “I have forgotten my password”
Subscribe
Subscribe to

Neurocirugía (English edition)

Purchase
Purchase article

Purchasing article the PDF version will be downloaded

Purchase now
Contact
Phone for subscriptions and reporting of errors
From Monday to Friday from 9 a.m. to 6 p.m. (GMT + 1) except for the months of July and August which will be from 9 a.m. to 3 p.m.
Calls from Spain
932 415 960
Calls from outside Spain
+34 932 415 960
Email
Idiomas
Neurocirugía (English edition)
Article options
Tools
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?