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Vol. 1. Issue 6.
Pages 401-409 (January 1990)
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Vol. 1. Issue 6.
Pages 401-409 (January 1990)
Hipofisitis granulomatosa
J. Sala, J.M. Izquierdo, E. Bráñez
Departamento de Cirugía (Neurocirugía) y de A. Patológica. Facultad de Medicina y Centro Médico de Asturias. Oviedo
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Resumen

Se describe un caso de hipofisítis granulomatosa en una mujer de 28 años, con síntomas de cefalea y diplopia ocasionada por una parálisis del nervio MOE del ojo izquierdo. Paradójicamente no presentaba alteraciones hormonales.

Los estudios radiológicos y la TAC no mostraban alteraciones patológicas. Solamente la Resonancia Magnética demostró un aumento de tamaño del contenido selar, que hacía sospechar un adenoma de hipófisis.

Fue operada y tratada con corticoides, mejorando progresivamente de sus molestias.

El estudio hitopatológico confirmó la existencia de una inflamación granulomatosa crónica e inespecífica en la hipófisis.

Palabras clave:
Hipófisis
granulomas
hipofisitis
adenoma hipófisis
Summary

We report a case of granulomatous hypophysitis in a 38 year old woman who suffered cephalea and dyplopia, caused by left abducens palsy. No relevant endocrine alteration was observed.

Plain x-ray films and C.T. were normal, but M.R.I. disclosed an enlarged sellar content, what was supossed to be a pituitary tumor.

Transphenoidal surgical exploration of the sella revealed a hypertrophic hypophysis, without adenomatous tissue.

Histopathological analysis of the taken samples showed definite signs of granulomatous hypophysitis.

After two months of corticoid treatment, dyplopia disappeared.

Key words:
Hypophysis
granuloma
hypophysitis
pituitary tumor

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