Journal Information
Vol. 25. Issue 3.
Pages 132-135 (May - June 2014)
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Vol. 25. Issue 3.
Pages 132-135 (May - June 2014)
Caso clínico
Metástasis medulares de gliosarcoma. Presentación de un caso y revisión de la literatura
Spinal cord metastasis from gliosarcoma. Case report and review of the literature
Carlos Asencio-Cortésa,
Corresponding author
casencio@santpau.cat

Autor para correspondencia.
, Cristian de Quintana-Schmidta, Pablo Clavel-Lariab, Ignasi Català Antúneza,b, Guillermo Montes Gracianoa, Joan Molet Teixidòa
a Servicio de Neurocirugía, Hospital Universitario de la Santa Creu i Sant Pau, Barcelona, España
b Servicio de Neurocirugía, Hospital Quirón, Barcelona, España
Article information
Abstract
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Tabla 1. Metástasis intramedulares de gliosarcoma
Resumen
Introducción

El gliosarcoma es un tumor cerebral primario infrecuente similar al glioblastoma multiforme. En contrapartida al glioblastoma multiforme, debido a su componente sarcomatoso, los gliosarcomas tienen mayor tendencia a realizar metástasis extracraneales (11% de los casos). A pesar de ello, las metástasis medulares del gliosarcoma cerebral primario son extremadamente infrecuentes.

Caso clínico

Se presenta el caso de una paciente intervenida de gliosarcoma cerebral que en el curso evolutivo de su enfermedad presenta una paraparesia, diagnosticándose e interviniéndose de metástasis medular de gliosarcoma. Realizamos una revisión sistemática de la literatura sobre los casos descritos de metástasis intramedular, sus características, el tratamiento realizado y el pronóstico.

Conclusiones

Únicamente se han descrito 4 casos de metástasis intramedular de gliosarcoma en la literatura. Se trata de una entidad infrecuente pero en la que debemos pensar ante la aparición de clínica medular en el curso evolutivo de un paciente con gliosarcoma cerebral.

Palabras clave:
Gliosarcoma
Metástasis
Médula espinal
Tratamiento
Supervivencia
Pronóstico
Abstract
Introduction

Gliosarcoma is a rare neoplasm of the central nervous system, similar to glioblastoma multiforme. In contrast to glioblastoma, it is characterised by its propensity for extracranial metastasis (11% of the cases) due to its sarcomatous component. Intramedullary metastasis from primary gliosarcoma is extremely rare.

Case report

A patient who had surgery for primary cerebral gliosarcoma developed paraparesis during the course of the disease. A magnetic resonance image showed an intramedullary spinal cord metastasis requiring surgical treatment. This article reviews the literature on intramedullary spinal cord metastasis from gliosarcoma, and highlights the characteristics, treatment and overall survival.

Conclusions

Only 4 cases of intramedullary gliosarcoma metastasis are described in the literature. This extremely rare entity should be suspected with the onset of spinal cord symptoms during the course of primary cerebral gliosarcoma.

Keywords:
Gliosarcoma
Metastasis
Spinal cord
Treatment
Survival
Prognosis

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