El gliosarcoma es un tumor cerebral primario infrecuente similar al glioblastoma multiforme. En contrapartida al glioblastoma multiforme, debido a su componente sarcomatoso, los gliosarcomas tienen mayor tendencia a realizar metástasis extracraneales (11% de los casos). A pesar de ello, las metástasis medulares del gliosarcoma cerebral primario son extremadamente infrecuentes.
Caso clínicoSe presenta el caso de una paciente intervenida de gliosarcoma cerebral que en el curso evolutivo de su enfermedad presenta una paraparesia, diagnosticándose e interviniéndose de metástasis medular de gliosarcoma. Realizamos una revisión sistemática de la literatura sobre los casos descritos de metástasis intramedular, sus características, el tratamiento realizado y el pronóstico.
ConclusionesÚnicamente se han descrito 4 casos de metástasis intramedular de gliosarcoma en la literatura. Se trata de una entidad infrecuente pero en la que debemos pensar ante la aparición de clínica medular en el curso evolutivo de un paciente con gliosarcoma cerebral.
Gliosarcoma is a rare neoplasm of the central nervous system, similar to glioblastoma multiforme. In contrast to glioblastoma, it is characterised by its propensity for extracranial metastasis (11% of the cases) due to its sarcomatous component. Intramedullary metastasis from primary gliosarcoma is extremely rare.
Case reportA patient who had surgery for primary cerebral gliosarcoma developed paraparesis during the course of the disease. A magnetic resonance image showed an intramedullary spinal cord metastasis requiring surgical treatment. This article reviews the literature on intramedullary spinal cord metastasis from gliosarcoma, and highlights the characteristics, treatment and overall survival.
ConclusionsOnly 4 cases of intramedullary gliosarcoma metastasis are described in the literature. This extremely rare entity should be suspected with the onset of spinal cord symptoms during the course of primary cerebral gliosarcoma.
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