Journal Information
Vol. 24. Issue 5.
Pages 220-224 (September - October 2013)
Share
Share
Download PDF
More article options
Vol. 24. Issue 5.
Pages 220-224 (September - October 2013)
Case report
Tumefactive multiple sclerosis requiring emergency craniotomy: Case report and literature review
Esclerosis múltiple pseudotumoral que precisa craneotomía urgente: caso clínico y revisión de la literatura
Pablo M. Munarriza,
Corresponding author
pablommunarriz@gmail.com

Corresponding author.
, Ana M. Castaño-Leona, Rafael Martinez-Pereza, Aurelio Hernandez-Lainb, Ana Ramosc, Alfonso Lagaresa
a Department of Neurosurgery, University Hospital 12 de Octubre, Complutense University of Madrid, School of Medicine, Madrid, Spain
b Department of Neuropathology, University Hospital 12 de Octubre, Complutense University of Madrid, School of Medicine, Madrid, Spain
c Department of Neuroradiology, University Hospital 12 de Octubre, Complutense University of Madrid, School of Medicine, Madrid, Spain
Article information
Abstract
Full Text
Bibliography
Download PDF
Statistics
Figures (3)
Show moreShow less
Abstract

Multiple sclerosis (MS) is a demyelinating disease of the central nervous system, characterized by focal neurological dysfunction with a relapsing and remitting course. Tumor-like presentation of MS (or “tumefactive”/“pseudotumoral” presentation) has been described before with a certain frequency; it consists of a large single plaque (>2cm) with presence of edema and mass effect and it is hard to distinguish from a brain tumor. However, we present a very rare case of a 53-year-old woman with a right temporal mass that turned out to be a MS plaque, who deteriorated within hours (brain herniation with loss of consciousness and unilateral mydriasis) and required an emergency craniotomy. We also present a review of the literature. It appears that only 4 cases of emergency craniotomy/craniectomy required in a patient with a tumor-like MS plaque have been reported before.

Keywords:
Multiple sclerosis
Tumefactive multiple sclerosis
Pseudotumoral multiple sclerosis
Resumen

La Esclerosis Múltiple (EM) es una enfermedad desmielinizante del sistema nervioso central, que se caracteriza por déficits neurológicos con un curso recurrente-remitente. La presentación pseudotumoral de la esclerosis múltiple ha sido descrita en la literatura con cierta frecuencia, se define como la presencia de una única placa desmielinizante grande (>2cm) con edema asociado y efecto de masa, que puede confundirse fácilmente con un tumor cerebral entre otros diagnósticos alternativos. Presentamos el caso de una mujer de 53 años con una lesión en el lóbulo temporal derecho que resultó ser una placa de desmielinización aguda, la singularidad del caso reside en que la paciente deteriora neurológicamente en pocas horas (coma y midriasis ipsilateral) requiriendo una intervención quirúrgica urgente. En la revisión de la literatura que hemos llevado a cabo, solo hemos encontrado publicados otros cuatro casos en los que un paciente con una placa pseudotumoral de EM precisase una craneotomía/craniectomía urgente.

Palabras clave:
Esclerosis múltiple
Esclerosis múltiple tumefacta
Esclerosis múltiple pseudotumoral

Article

These are the options to access the full texts of the publication Neurocirugía (English edition)
Member
Member of the Sociedad Española de Neurocirugía

If it is the first time you have accessed you can obtain your credentials by contacting Elsevier Spain in suscripciones@elsevier.com or by calling our Customer Service at902 88 87 40 if you are calling from Spain or at +34 932 418 800 (from 9 to 18h., GMT + 1) if you are calling outside of Spain.

If you already have your login data, please click here .

If you have forgotten your password you can you can recover it by clicking here and selecting the option ¿I have forgotten my password¿.

Subscriber
Subscriber

If you already have your login data, please click here .

If you have forgotten your password you can you can recover it by clicking here and selecting the option “I have forgotten my password”
Subscribe
Subscribe to

Neurocirugía (English edition)

Purchase
Purchase article

Purchasing article the PDF version will be downloaded

Price 19.34 €

Purchase now
Contact
Phone for subscriptions and reporting of errors
From Monday to Friday from 9 a.m. to 6 p.m. (GMT + 1) except for the months of July and August which will be from 9 a.m. to 3 p.m.
Calls from Spain
932 415 960
Calls from outside Spain
+34 932 415 960
Email
Idiomas
Neurocirugía (English edition)
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?