El síndrome de Muir-Torre es una enfermedad genética que se caracteriza por la aparición de neoplasias sebáceas con neoplasias viscerales y, en una menor incidencia, genitourinarias. Las metástasis cerebrales de tumores prostáticos sin evidencia de lesión sistémica son poco frecuentes y en el tronco cerebral son excepcionales.
Caso clínicoPresentamos un paciente de 48 años con una metástasis única en tronco cerebral de un adenocarcinoma prostático previamente diagnosticado de un síndrome de Muir-Torre. Se realizó por una biopsia estereotáctica para su diagnóstico.
ConclusiónLa metástasis única de adenocarcinoma de próstata a nivel troncoencefálico sin afectación sistémica es prácticamente excepcional. Las posibilidades diagnósticas de inicio en el contexto de un síndrome de Muir-Torre obligan la realización de biopsia, y la estereotaxia es el método de elección.
Muir-Torre syndrome is a genetic disease characterised by the association of sebaceous neoplasms with visceral neoplasms, mainly colorectal cancer and secondly urogenital tumours. Metastases from prostate tumours without systemic disease are rare in the brain and exceptional in the brainstem.
Case reportWe present a 48-year old male, with a single brainstem metastasis from a prostate adenocarcinoma, who had previously been diagnosed with Muir-Torre syndrome. Diagnostic stereotactic biopsy was performed.
ConclusionSingle metastasis from a prostate adenocarcinoma in the brainstem without systemic disease is exceptional. Due to the different diagnostic possibilities, biopsy should be performed in order to obtain a diagnosis, especially in the context of Muir-Torre syndrome.
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