Se presentan dos casos de macroadenomas no funcionantes grandes que, tras su extirpación parcial por vía transesfenoidal, sufrieron un infarto del resto tumoral residual, con resultado de aumento de su volumen, compresión de las estructuras vecinas y deterioro neurológico de los pacientes. Ambos fueron reintervenidos por vía transcraneal para conseguir la extirpación completa de sus tumores. Se revisa la bibliografía en busca de las claves para prevenir esta complicación.
We report two cases of large macroadenomas that, after a transsphenoidal partial resection, suffered necrosis and swelling of the residual tumor, with increase of its volume, compression of neighboring structures and neurological deterioration. The literature is reviewed looking for possible pathophysiological mechanism and prevention.
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