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Case Report
DOI: 10.1016/j.neucir.2017.03.004
Teratoma of the nervous system: A case series
Teratoma del sistema nervioso: serie de casos
Hussein Algahtania,
Corresponding author
halgahtani@hotmail.com

Corresponding author.
, Bader Shirahb, Ahad Abdullahc, Abdulrahman Bazaidc
a King Abdulaziz Medical City/King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia
b King Abdullah International Medical Research Center/King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia
c Batterjee Medical College, Jeddah, Saudi Arabia
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Received 07 February 2017, Accepted 29 March 2017
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Abstract

Teratoma is a common form of germ cell tumors composed of multiple tissues foreign to the site in which arise with a histological representation of all three germ cell layers. Intracranial teratomas are very rare. In this study, we report three cases of intracranial teratomas with an interesting clinical course, neuroradiology, and outcome. In addition, we review the literature and convey important messages to the neuroscience community regarding issues related to the management of these rare tumors. The present cases are interesting examples of intracranial teratoma in terms of location of the tumor and neuroimaging findings. Delay in surgical intervention may complicate the course of the disease with progressive enlargement of tumors and development of complication including hydrocephalus. Using endoscopic surgical techniques may emerge as the preferred intervention option as compared to other traditional methods. We recommend the establishment of a national and international registry for intracranial tumors.

Keywords:
Teratoma
Germ cell tumor
Brain tumor
Pineal gland
Cerebral hemisphere
Posterior fossa
Resumen

El teratoma es un tipo frecuente de tumor de células germinales compuesto por múltiples tejidos ajenos a la zona en que aparecen con una representación histológica de las 3 capas de células germinales. Los teratomas intracraneales son muy poco frecuentes. En este estudio, se presentan 3 casos de teratomas intracraneales con una evolución clínica, neurorradiología y resultado interesantes. Además, se revisa la bibliografía y se difunde un mensaje importante a la comunidad de las neurociencias respecto a los problemas relacionados con el tratamiento de estos tumores raros. Estos casos son ejemplos interesantes de teratoma intracraneal en términos de localización de los hallazgos tumorales y de neuroimagen. El retraso en la intervención quirúrgica puede complicar la evolución de la enfermedad con la ampliación progresiva de los tumores y el desarrollo de complicaciones, especialmente hidrocefalia. El uso de técnicas quirúrgicas endoscópicas aparece como la opción de intervención preferida en comparación con otros métodos tradicionales. Se recomienda el establecimiento de un registro nacional e internacional de tumores intracraneales.

Palabras clave:
Teratoma
Tumor de células germinales
Tumor cerebral
Glándula pineal
Hemisferio cerebral
Fosa posterior

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