TY - JOUR T1 - Prognosis of atypical teratoid rhabdoid tumors (AT/RT) treated with multimodal therapy protocols. Report of our series JO - Neurocirugía (English edition) T2 - AU - Valencia-Moya,Alfonso AU - González-García,Laura AU - Ros-López,Bienvenido AU - Acha-García,Tomás AU - Weil-Lara,Bernardo AU - Obando-Pacheco,Pablo AU - Arráez-Sánchez,Miguel Ángel SN - 11301473 M3 - 10.1016/j.neucir.2015.01.003 DO - 10.1016/j.neucir.2015.01.003 UR - https://www.revistaneurocirugia.com/es-prognosis-atypical-teratoid-rhabdoid-tumors-articulo-S1130147315000202 AB - ObjectiveAtypical teratoid rhabdoid tumors (AT/RT) of the central nervous system are rare, very aggressive embryological tumors, typically diagnosed in young patients and having a low survival rate after diagnosis. The aim of this study was to emphasize, based on the latest results in the literature, the need for protocols for multidisciplinary treatment in these patients. Material and methodsWe report our series of 3 cases treated, diagnosed and followed up between 2009 and 2014. They were treated with multimodal therapy protocols (Rhabdoid SIOP-2007 and European Rhabdoid Registry EU-RHAB-2010). In addition, we carried out a literature review. ResultsTwo of our 3 cases (supratentorial and spinal tumors) did not show any progression of the disease after long follow-up, in contrast with most of the cases available in the literature. The second patient had a shorter survival. ConclusionsPatient age at the time of diagnosis, supratentorial location of the mass and fewer complications with adjuvant treatments seem to be factors yielding good prognosis for AT/RT tumors. In agreement with the latest international protocols, multidisciplinary treatment is the ideal treatment, consisting of radiotherapy and chemotherapy after complete tumor resection. ER -