Journal Information
Vol. 17. Issue 1.
Pages 60-63 (January 2006)
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Vol. 17. Issue 1.
Pages 60-63 (January 2006)
Complete surgical resection of high-grade astroblastoma with long time survival: case report and review of the literature
Astroblastoma de alto grado con supervivencia prolongada tras resección completa: descripción de un caso y revisión de la literatura
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P. Miranda
, R.D. Lobato, P.A. Gómez
Servicios de Neurocirugía. Hospital 12 de Octubre. Madrid
A. Cabello*, A. Martínez de Aragón**
* Servicios de Neuropatología. Hospital 12 de Octubre. Madrid
** Servicios de Neurorradiología. Hospital 12 de Octubre. Madrid
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Summary

Astroblastoma is a rare glial neoplasm of unknown origin and uncertain prognosis. It usually presents in young adults as a well circumscribed hemispheric mass, often associated with a cystic component. The histological features of astroblastoma are the presence of typical astroblastic perivascular pseudorosettes and perivascular hyalinization. Two different subtypes of astroblastoma have been defined based upon histological characteristics. Prognosis, however, sometimes is in contradiction with the pathological appearance and seems to be more closely related to the grade of surgical resection. We present a new case of a patient with a high-grade astroblastoma with a long survival time, in whom complete surgical resection was confirmed by an early postoperative MRI.

Key words:
Astroblastoma
Glial tumor
Treatment
Prognosis
Abreviaturas:
CT
GFAB
MRI
Resumen

El astroblastoma es un tumor glial infrecuente de origen desconocido y pronóstico incierto. Habitualmente se presenta en adultos como una masa hemisférica bien definida, presentando a menudo un componente quístico. Las características histopatológicas de este tumor incluyen la presencia de pseudorrosetas perivasculares astroblásticas típicas y la hialinización perivascular. Se han distinguido dos tipos de astroblastoma en relación a la malignidad histológica. Sin embargo, el pronóstico en ocasiones no guarda relación directa con el tipo histológico y parece más dependiente del grado de resección quirúrgica. Presentamos el caso de una paciente con un astroblastoma de alto grado con supervivencia prolongada, en el cual la resección quirúrgica completa se demostró mediante resonancia magnética postoperatoria precoz.

Palabras clave:
Astroblastoma
Tumor glial
Tratamiento
Pronóstico

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